cAIMP
Product Specifications
UNSPSC Description
cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L[1].
Target Antigen
IFNAR; NF-κB
Type
Reference compound
Related Pathways
Immunology/Inflammation;NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/caimp.html
Smiles
O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP(O)(OC[C@]3([H])[C@@]([C@H]([C@H](N4C5=C(C(N=CN5)=O)N=C4)O3)O)([H])OP(O)(OC2)=O)=O)N6C7=NC=NC(N)=C7N=C6
Molecular Weight
659.40
References & Citations
[1]Chunyong Ding, et al. Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway. Acta Pharm Sin B. 2020 Dec;10(12):2272-2298.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134375/cAIMP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134375/
Clinical Information
No Development Reported
CAS Number
1507367-51-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
EM1245 96 Tests
Mouse NTRK2 (Neurotrophic Tyrosine Kinase Receptor Type 2) ELISA Kit
Ask
View Details 
