Pentosidine ELISA Kit

Pentosidine is a carbohydrate-derived advanced glycation end product (AGEs) that is considerably elevated in uremic patients. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. BioVision’s Pentosidine ELISA Kit is based on Competitive ELISA principle. The micro-plate provided in this kit has been pre-coated with Pentosidine. During the reaction, Pentosidinein the samples or standard competes with Pentosidine coated on the plate for binding to the anti-Pentosidine antibody. Then Horseradish Peroxidase (HRP) conjugate is added to each micro plate well, and TMB substrate is for color development. There is a negative correlation between the OD value of samples and the concentration of Lipoxin A4. The concentration of Pentosidine in the samples can be calculated by comparing the OD of the samples to the standard curve.