FB23-2
FB23-2 is a potent FTO (fat mass and obesity-associated) inhibitor. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity (IC50 = 2.6 µM). Mimicking FTO depletion, FB23-2 dramatically suppresses proliferation and promotes the differentiatiopoptosis of human acute myeloid leukemia (AML) cell line cells and primary blast AML cells in vitro.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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