Famotidine
Famotidine is a competitive inhibitor of histamine H2-receptor located on the basolateral membrane of the parietal cells. Famotidine inhibits histamine-induced acid secretion in isolated canine parietal cells with an IC₅₀ of 0.6 µM. It suppresses histamine-induced gastric acid secretion in dogs and anesthetized rats with ID₅₀ values of 10 and 400 µg/kg, respectively. It is used to treat ulcers, gastroesophageal reflux disease and heartburn. Famotidine is also being investigated in clinical trials for treatment against COVID-19.
Product Specifications
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36months
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