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TGN-020

TGN-020 is an inhibitor of aquaporin 4 (AQP4), the most abundant water channel in brain. It inhibits AQP4 inhibitor with an IC₅₀ of 3 μM in vitro. Pretreatment with the AQP4 inhibitor TGN-020 significantly reduces ischemic cerebral edema associated with focal cerebral ischemia in a mouse model.

Product Specifications

Shipping Conditions

RT

Storage Conditions

-20ºC

Shelf Life

36months

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