Wogonoside

Wogonoside is a flavonoid with antioxidant, anti-cancer and anti-angiogenic activity. Wogonoside inhibits the growth of U937 and HL-60 cells cells. It arrests the cell cycle at the G0/G1 phase and decreases the G2/M and S phases in these cells in a dose dependent manner at concentrations of 50 μM, 100 μM, and 150 μM. It inhibits LPS-induced angiogenesis by inhibiting the toll-like receptor 4 upregulation.