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SAMHD1 (phospho-Thr592) rabbit pAb

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],

Product Specifications

Background

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

Product Name Alternative

SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)

UniProt

Q9Y3Z3

Swiss Prot

Q9Y3Z3

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized phosho peptide around human SAMHD1 (Thr592)

Target

SAMHD1

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Buffer

-20°C/1 year

Molecular Weight

72kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

72kD

Fragment

IgG

Subcellular Location

Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .

Other Product Names

SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)

Gene ID (Human)

25939

Available Sizes

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