KwFwLL-NH2
KwFwLL-NH2, a hexapeptide, is a ghrelin receptor ligand. KwFwLL-NH2 can act as a specific inverse agonist at the ghrelin receptor but with moderate potency (EC50=45.6 nM) [1].
Product Specifications
CAS Number
942266-38-8
UNSPSC
12352209
Target
GHSR
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kwfwll-nh2.html
Smiles
O=C(N[C@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](CC4=CNC5=CC=CC=C45)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Molecular Formula
C49H66N10O6
Molecular Weight
891.11
References & Citations
[1]Els S, et al. An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. J Med Chem. 2012 Sep 13;55 (17) :7437-49.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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