HCAIX/XII-IN-11

HCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII with a Ki value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaix-xii-in-11.html

Solubility

10 mM in DMSO

Smiles

CC1=C(N=NN1C2=CC=C(C=C2)F)C(/C=C(C(O)=O)\O)=O

Molecular Formula

C13H10FN3O4

Molecular Weight

291.23

References & Citations

[1]Siwach K, et al. 1,2,3-Triazole-based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition. Arch Pharm (Weinheim) . 2024 Mar;357 (3) :e2300372.