Isoharringtonine
Isoharringtonine is a natural alkaloid that can be purified from Cephalotaxus koreana Nakai. Isoharringtonine can inhibit cancer cell proliferation and migration, and induce cancer cell apoptosis. Isoharringtonine can be used for the research of cancers[1][2].
Product Specifications
CAS Number
26833-86-3
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isoharringtonine.html
Solubility
10 mM in DMSO
Smiles
COC([C@@H](O)[C@@](CCC(C)C)(O)C(O[C@H]1[C@]2([H])[C@]3(C=C1OC)N(CCC3)CCC4=CC(OCO5)=C5C=C42)=O)=O
Molecular Formula
C28H37NO9
Molecular Weight
531.59
References & Citations
[1]Lee JH, et al. Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway. Biomolecules. 2020 Nov 6;10 (11) :1521. |[2]Chen W, et al. Isoharringtonine inhibits breast cancer stem-like properties and STAT3 signaling. Biomed Pharmacother. 2018 Jul;103:435-442.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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