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HbBs Antibody

Hemoglobin beta S antibody

Product Specifications

Product Name Alternative

Mouse anti-HbS antibody, mouse anti-hemoglobin antibody, Hemoglobin beta subunit sickle mutant, HBS, HBBs, HbS Antibody, Sickle Cell Disease (SCD)

UniProt

P68871

Reactivity

Human

Immunogen

Anti-Hemoglobin beta S Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb β-subunit conjugated to KLH.

Target

HbBs

Clonality

Monoclonal

Clone

23E5.H6.G6.C1.H7.F7.G9.F6

Conjugation

Unconjugated

Concentration

1.00 mg/ml

Dilution

ELISA: 1:20,000, WB: 1ug/mL

Purity

This protein A purified mouse monoclonal antibody reacts specifically with human HbS beta sickle isoform. Anti-HbS is purified from tissue culture supernatant by protein A purification. Blast analysis shows 100% homology to Human, Pan troglodytes, Pan paniscus, Gorilla gorilla gorilla, and Hylobates lar. This antibody does not react with the HbA, HbF, HbC, or HbA-2 isoform.

Form

Liquid (sterile filtered)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Anti-Hemoglobin beta S (MOUSE) antibody has been tested by ELISA, SDS-Page, and western blot. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa in appropriate lysates.

Tested Applications

ELISA, WB

Host or Source

Mouse

Preservative

Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: None; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

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