PKC-theta inhibitor 2 (hydrochloride)
PKC-theta inhibitor 2 hydrochloride is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1].
Product Specifications
CAS Number
2253640-49-0
UNSPSC
12352005
Hazard Statement
H303-H315-H319-H335
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pkc-theta-inhibitor-2-hydrochloride.html
Smiles
FC(F)(F)OC1=CC=CC=C1CNC2=NC=C([N+]([O-])=O)C(NCC3CCC(CN)CC3)=N2.Cl
Molecular Formula
C20H26ClF3N6O3
Molecular Weight
490.91
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17 (1) :225-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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