FANCE Antibody
FANCE antibody
Product Specifications
Product Name Alternative
Rabbit anti-FANCE antibody, FANC-E, FANC E, FACE antibody, FAE antibody, Fanconi anemia group E protein, Fanconi anemia complementation group E antibody
UniProt
Q9HB96
Reactivity
Human
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. LocusLink ID 2178; SwissProt accession number Q9HB96
Target
FANCE
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Concentration
1.0 mg/mL
Dilution
ELISA: 1:10,000 - 1:50,000, WB: 1:500- 1:2,000
Purity
This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
Form
Liquid (sterile filtered)
Storage Conditions
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Notes
For research use only.
Applications Notes
This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Tested Applications
ELISA, WB
NCBI Accession Number
NP_068741.1
Host or Source
Rabbit
Preservative
Preservative: 0.01% (w/v) Sodium Azide. Stabilizer: None; Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Isotype
IgG
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