Mutanocyclin
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse[1].
Product Specifications
CAS Number
[875455-92-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mutanocyclin.html
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1[C@@H](CC(C)C)NC(O)=C1C(C)=O
Molecular Formula
C10H15NO3
Molecular Weight
197.23
Precautions
H302, H315, H319
References & Citations
[1]Tao L, et al. Streptococcus mutans suppresses filamentous growth of Candida albicans through secreting mutanocyclin, an unacylated tetramic acid. Virulence. 2022 Dec;13 (1) :542-557.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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