N-3-oxo-dodecanoyl-L-homoserine lactone
Selected Variant
HY-114544A-01
Size: 5 mg
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex[1][2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells[3].
Product Specifications
CAS Number
168982-69-2
Product Name Alternative
OdDHL
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Bacterial; Caspase; ERK; NF-κB; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-3-oxo-dodecanoyl-l-homoserine-lactone.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O
Molecular Formula
C16H27NO4
Molecular Weight
297.39
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
Price
Frequently Asked Questions
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