Calcium mesoxalate
Calcium mesoxalate blocks HIV-1 RT (IC50: 2.2 μM) [1][2].
Product Specifications
CAS Number
[21085-60-9]
Product Name Alternative
Ketomalonic acid (calcium) ; Mesoxalic acid (calcium) ; Oxomalonic acid (calcium)
UNSPSC
12352300
Hazard Statement
H302, H315, H319, H335
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ketomalonic-acid-calcium.html
Solubility
10 mM in DMSO
Smiles
O=C(C([O-])=O)C([O-])=O.[Ca+2]
Molecular Formula
C3CaO5
Molecular Weight
156.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Jean A Bernatchez, et al. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. J Biol Chem. 2015 Jan 16;290 (3) :1474-84.|[2]W R Davis, et al. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39 (46) :14279-91.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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