Cortistatin-17 (human)

Cortistatin-17 (human) is a somatostatin neuropeptide with potential for studying diseases such as cancer, inflammation, autoimmunity, fibrosis, and pain[1][2].

Product Specifications

CAS Number

[189450-19-9]

UNSPSC

12352209

Target

Somatostatin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cortistatin-17-human.html

Purity

99.04

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)CC2=CC=CC=C2)=O)CO)=O)CO)=O)C(N[C@H](C(O)=O)CCCCN)=O)NC([C@H]3N(CCC3)C([C@H](CCSC)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)=O)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)N[C@H]1CC6=CNC7=CC=CC=C67

Molecular Formula

C96H139N27O24S3

Molecular Weight

2151.49

References & Citations

[1]Spier AD, et al. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Brain Res Rev. 2000 Sep;33 (2-3) :228-41. |[2]Campos-Salinas J, et al. Therapeutic Effect of a Latent Form of Cortistatin in Experimental Inflammatory and Fibrotic Disorders. Pharmaceutics. 2022 Dec 13;14 (12) :2785.