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Neuromedin S (human)

Neuromedin S (human) is a neuropeptide that contains 33 amino acids. Neuromedin S (human) has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis[1].

Product Specifications

CAS Number

1138204-27-9

UNSPSC

12352209

Target

G protein-coupled Bile Acid Receptor 1; Neuromedin U Receptor (NMUR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neuromedin-s-human.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC(C)C)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=CC=C4)NC([C@H]5N(C([C@H](CCCNC(N)=N)NC(CNC([C@H](CC6=CNC7=CC=CC=C67)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CC8=CNC=N8)NC([C@H](CC(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](CC9=CC=CC=C9)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](C)NC([C@H]([C@H](O)C)NC(CNC([C@H](CO)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC5)=O)=O)=O)=O)=O)=O)CCC1)=O)=O

Molecular Formula

C173H264N52O45

Molecular Weight

3792.27

References & Citations

[1]Martin R Edelmann , et al. Tritium Labeling of Neuromedin S by Conjugation with [3H] N-Succinimidyl Propionate. ACS Omega. 2023, 8, 2.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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