Prothracarcin

Prothracarcin is an antibiotic with antitumor activity that exerts its tumor cell toxicity by covalently binding to the C-2 amino group of guanine residues in the minor groove of DNA. Prothracarcin also shows antibacterial activity against Gram-positive bacteria and some Gram-negative bacteria such as Escherichia coli[1].

Product Specifications

CAS Number

[81542-99-6]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/prothracarcin.html

Smiles

O=C1N2C(C=NC3=CC=CC=C13)C/C(C2)=C\C

Molecular Formula

C14H14N2O

Molecular Weight

226.27

References & Citations

[1]Fotso, et al. Limazepines A− F, Pyrrolo [1, 4] benzodiazepine Antibiotics from an Indonesian Micrococcus sp. Journal of natural products 72.4 (2009) : 690-695.