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Fexagratinib (Standard)

Selected Variant

HY-13330R-01

Size: 5 mg

Fexagratinib (Standard) is the analytical standard of Fexagratinib. This product is intended for research and analytical applications. Fexagratinib (AZD4547; ADSK091) is a potent inhibitor of the FGFR family with IC50s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

Product Specifications

CAS Number

1035270-39-3

Product Name Alternative

AZD4547 (Standard) ; ADSK091 (Standard)

UNSPSC

12352005

Target

FGFR; Reference Standards

Type

Reference Standards

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fexagratinib-standard.html

Smiles

C[C@H](C1)N[C@@H](C)CN1C2=CC=C(C(NC3=NNC(CCC4=CC(OC)=CC(OC)=C4)=C3)=O)C=C2

Molecular Formula

C26H33N5O3

Molecular Weight

463.57

References & Citations

[1]Gavine PR, et al. AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res, 2012, 72 (8), 2045-2056.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Price

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