Heptaminol (hydrochloride) (Standard)

Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride) . This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels[1][2][3].

Product Specifications

CAS Number

[543-15-7]

Product Name Alternative

RP-2831 hydrochloride (Standard)

UNSPSC

12352211

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/heptaminol-hydrochloride-standard.html

Smiles

CC(O)(C)CCCC(N)C.[H]Cl

Molecular Formula

C8H20ClNO

Molecular Weight

181.70

References & Citations

[1]Pourrias B, et al. Heptaminol chlorhydrate: new data. Ann Pharm Fr. 1991;49 (3) :127-138.|[2]Reiter M. Die indirekt sympathicomimetische Wirkung von Heptaminol auf den Herzmuskel [Indirect sympathomimetic effect of heptaminol on heart muscle]. Naunyn Schmiedebergs Arch Pharmakol. 1970;267 (2) :114-22. German.|[3]Chung JF, et al. NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil. Oncotarget. 2016 Jul 26;7 (30) :47576-47585.