8-Pcpt-cGMP (sodium)

8-Pcpt-cGMP sodium is the sodium salt form of 8-Pcpt-cGMP (HY-137016) . 8-Pcpt-cGMP sodium is an agonist for cyclic nucleotide-gated (CNG) channel with an EC50 of 0.5 μM. 8-Pcpt-cGMP sodium exhibits good membrane permeability. 8-Pcpt-cGMP sodium can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction[1].

Product Specifications

CAS Number

[51239-26-0]

UNSPSC

12352005

Target

HCN Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/8-pcpt-cgmp-sodium.html

Purity

99.0

Solubility

H2O : 25 mg/mL (ultrasonic; warming)

Smiles

O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O[Na])=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl

Molecular Formula

C16H14ClN5NaO7PS

Molecular Weight

509.79

References & Citations

[1]Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10 (1) :53-64.