14-3-3-IN-1
14-3-3-IN-1 (Compound 2) is an inhibitor for 14-3-3 proteins in Arabidopsis thaliana, with an IC50 of 1.21 μM. 14-3-3-IN-1 exhibits different inhibitory activities against different 14-3-3 isomers. 14-3-3-IN-1 promotes the closure of stomata on leaves[1].
Product Specifications
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/plant-14-3-3-in-1.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C(C=CC=C2)=C(O)C(S(C)(=O)=O)=C1C(OCC(N3CCC4=C3C=CC=C4)=O)=O
Molecular Formula
C22H19NO7S
Molecular Weight
441.45
References & Citations
[1]Nishiyama K, et al., Discovery of a Plant 14-3-3 Inhibitor Possessing Isoform Selectivity and In Planta Activity. Angew Chem Int Ed Engl. 2024 Apr 24:e202400218.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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