BKM-570
BKM-570 is a nonpeptide bradykinin antagonist with anticancer effects. BKM-570 can be used in the study of lung cancer, prostate cancer and ovarian cancer[1].
Product Specifications
CAS Number
259885-54-6
UNSPSC
12352005
Target
Bradykinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bkm-570.html
Smiles
O=C([C@@H](NC(/C=C/C1=C(C(F)=C(C(F)=C1F)F)F)=O)CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl)NC4CC(C)(C)NC(C)(C)C4
Molecular Formula
C34H34Cl2F5N3O3
Molecular Weight
698.55
References & Citations
[1]Stephanie Jutras, et al. Strong cytotoxic effect of the bradykinin antagonist BKM-570 in ovarian cancer cells--analysis of the molecular mechanisms of its antiproliferative action. FEBS J. 2010 Dec;277 (24) :5146-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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