Caspase-1, Human, Recombinant, E. coli

<strong>Caspase-1, Human, Recombinant, E. coli</strong>_x000D_ <strong>Catalog number:</strong> B2018846_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 3000 U_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> IL-1β Converting Enzyme, ICE_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ. Novel role of PKR in inflammasome activation and HMGB1 release Nature. 2012 Aug 30;488(7413):670-4._x000D_ 2: Mattiuz G, Nicolò S, Antonelli A, Giani T, Baccani I, Cannatelli A, Clemente AM, Castronovo G, Tanturli M, Cozzolino F, Rossolini GM, Torcia MG. mcr-1 Gene Expression Modulates the Inflammatory Response of Human Macrophages to Escherichia coli Infect Immun. 2020 Jul 21;88(8):e00018-20._x000D_ 3: Bibo-Verdugo B, Joglekar I, Karadi Giridhar MN, Ramirez ML, Snipas SJ, Clark AC, Poreba M, Salvesen GS. Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold J Biol Chem. 2022 Jun;298(6):101931._x000D_ 4: Verma V, Kumar P, Gupta S, Yadav S, Dhanda RS, Thorlacius H, Yadav M. α-Hemolysin of uropathogenic E. coli regulates NLRP3 inflammasome activation and mitochondrial dysfunction in THP-1 macrophages Sci Rep. 2020 Jul 28;10(1):12653._x000D_ 5: Zhang S, Ma L, Song F, Wang D, Shi K, Li Y, Zeng J, Wang Y. Pyroptosis of Macrophages Induced by Clostridium perfringens Beta-1 Toxin Toxins (Basel). 2023 May 29;15(6):366._x000D_ 6: Arlehamn CS, Evans TJ. Pseudomonas aeruginosa pilin activates the inflammasome Cell Microbiol. 2011 Mar;13(3):388-401._x000D_ 7: Park JA, Kim KW, Kim SI, Lee SK. Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells Eur J Biochem. 1998 Oct 1;257(1):242-8._x000D_ 8: Reis MI, do Vale A, Pereira PJ, Azevedo JE, Dos Santos NM. Caspase-1 and IL-1β processing in a teleost fish PLoS One. 2012;7(11):e50450._x000D_ 9: Hong J, Bae S, Jhun H, Lee S, Choi J, Kang T, Kwak A, Hong K, Kim E, Jo S, Kim S. Identification of constitutively active interleukin 33 (IL-33) splice variant J Biol Chem. 2011 Jun 3;286(22):20078-86._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29523140">10: Hu M, Zhao W, Li H, Gu J, Yan Q, Zhou X, Pan Z, Cui G, Jiao X. Immunization with recombinant Salmonella expressing SspH2-EscI protects mice against wild type Salmonella infection BMC Vet Res. 2018 Mar 9;14(1):79. </a>_x000D_ _x000D_ <strong>Products Related to Caspase-1, Human, Recombinant, E. coli can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>