Fluorogenic Caspase 3 Substrate 1

<strong>Fluorogenic Caspase 3 Substrate 1</strong>_x000D_ <strong>Catalog number:</strong> B2011257_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 729.7 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Caspase 3 Substrate, Fluorogenic, Apopain substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Mackay M, Pérez-López AM, Bradley M, Lilienkampf A. Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates Mol Biosyst. 2016 Mar;12(3):693-6._x000D_ 2: Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis Nat Protoc. 2010 Feb;5(2):294-302._x000D_ 3: Fuente-Garcia C, Sentandreu E, Aldai N, Sentandreu MA. Optimization of a fluorogenic assay to determine caspase 3/7 activity in meat extracts Food Sci Technol Int. 2022 Mar;28(2):128-134._x000D_ 4: Seol JG, Park WH, Kim ES, Jung CW, Hyun JM, Lee YY, Kim BK. Potential role of caspase-3 and -9 in arsenic trioxide-mediated apoptosis in PCI-1 head and neck cancer cells Int J Oncol. 2001 Feb;18(2):249-55._x000D_ 5: Fahy RJ, Doseff AI, Wewers MD. Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1 J Immunol. 1999 Aug 15;163(4):1755-62._x000D_ 6: Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury Neuroscience. 2000;99(2):333-42._x000D_ 7: Mandlekar S, Yu R, Tan TH, Kong AN. Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells Cancer Res. 2000 Nov 1;60(21):5995-6000._x000D_ 8: Tinsley KW, Cheng SL, Buchman TG, Chang KC, Hui JJ, Swanson PE, Karl IE, Hotchkiss RS. Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis Shock. 2000 Jan;13(1):1-7._x000D_ 9: Fan J, Cheney PP, Bloch S, Xu B, Liang K, Odonkor CA, Edwards WB, Basak S, Mintz R, Biswas P, Achilefu S. Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3 Curr Anal Chem. 2021;17(8):1182-1193._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17045246">10: Sakaue M, Motoyama Y, Yamamoto K, Shiba T, Teshima T, Chiba K. Quantitative measurement of caspase-3 activity in a living starfish egg Biochem Biophys Res Commun. 2006 Dec 1;350(4):878-83. </a>_x000D_ _x000D_ <strong>Products Related to Fluorogenic Caspase 3 Substrate 1 can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>