KB-R7943
KB-R7943 (compound 1) is an inhibitor of sodium-calcium exchanger with an IC50 value of 5.1 μM. KB-R7943 can be used as a tool in heart and renal failure models[1].
Product Specifications
CAS Number
[182004-64-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Na+/Ca2+ Exchanger
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/kb-r7943.html
Smiles
NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N
Molecular Formula
C16H17N3O3S
Molecular Weight
331.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Takahiro Kuramochi, et al. Discovery of N- (3-{4-[ (3-fluorobenzyl) oxy]phenoxy}propyl) -2-pyridin-4-ylacetamide as a potent and selective reverse NCX inhibitor. Chem Pharm Bull (Tokyo) . 2005 Aug;53 (8) :1043-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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