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KB-R7943

KB-R7943 (compound 1) is an inhibitor of sodium-calcium exchanger with an IC50 value of 5.1 μM. KB-R7943 can be used as a tool in heart and renal failure models[1].

Product Specifications

CAS Number

182004-64-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Na+/Ca2+ Exchanger

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/kb-r7943.html

Smiles

NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N

Molecular Formula

C16H17N3O3S

Molecular Weight

331.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Takahiro Kuramochi, et al. Discovery of N- (3-{4-[ (3-fluorobenzyl) oxy]phenoxy}propyl) -2-pyridin-4-ylacetamide as a potent and selective reverse NCX inhibitor. Chem Pharm Bull (Tokyo) . 2005 Aug;53 (8) :1043-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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