Cepadacursen (sodium)
Cepadacursen sodium is a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. Cepadacursen sodium can be used for hypercholesterolemia treatment and the prevention of atherosclerotic cardiovascular disease (ASCVD) .
Product Specifications
CAS Number
2252375-14-5
Product Name Alternative
CIVI007 (sodium)
UNSPSC
12352208
Target
PCSK9
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cepadacursen-sodium.html
Solubility
10 mM in H2O
Smiles
[Cepadacursen(sodium)]
Molecular Formula
C227H296N72Na16O116P16S16
Molecular Weight
6913.93 (free acid)
References & Citations
[1]Chen W, Wu X, Hu J, et al. The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7. Cardiovasc Diabetol. 2024;23 (1) :21. Published 2024 Jan 9. doi:10.1186/s12933-024-02119-z
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Frequently Asked Questions
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