MUC5AC Antibody
Mouse monoclonal antibody to MUC5AC, this monoclonal antibody (MAb) recognizes the peptide core of gastric mucin M1 (identified as MUC5AC, ~1,000 kDa) . The epitope is sensitive to β‐mercaptoethanol and protease digestion, but resistant to periodate treatment. The antibody reacts with normal gastric epithelium throughout the human gastrointestinal tract, as well as with precancerous and cancerous colon tissues; however, it does not stain normal adult colonic mucosa. Positive reactivity is also observed in fetal colonic mucosa. The reappearance of gastric mucin immunoreactivity during colorectal carcinogenesis corresponds to the re‐expression of the peptide epitope characteristic of gastric (or fetal colonic) mucins.
Product Specifications
Product Name Alternative
UniProt
P98088
Reactivity
Feline, Gallus, Human, Mammal, Monkey, Mouse, Porcine, Rabbit, Rat
Immunogen
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le (a-b) patient
Target
MUC5AC
Clonality
Monoclonal
Clone
SPM297
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Immunology & Inflammation, Infectious Disease & Virology
Dilution
FACS: 0.5-1 μg/million cells, IF/ICC: 1-2 μg/ml, IHC-P: 1-2 μg/ml
Form
Molecular Weight
1,000 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
MUC5AC (Mucin 5AC / Gastric Mucin)
Tested Applications
FC, IF, IHC
Host or Source
Mouse
Isotype
IgG1 / Kappa
Available Sizes
Frequently Asked Questions
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