Fosaprepitant-d4 (dimeglumine)
Fosaprepitant-d4 (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant. Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).
Product Specifications
Product Name Alternative
MK-0517-d4; L785298-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Neurokinin Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology; Cancer
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C37H52D4F7N6O16P
Molecular Weight
1008.86
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF405S conjugate, 0.1mg/mL
CD10 (CB-CALLA), CF640R conjugate, 0.1mg/mL
S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis) (CPTC-S100A4-3), CF594 conjugate, 0.1mg/mL
Calretinin / Calbindin 2 (Mesothelioma Marker) (CALB2/2603), CF405S conjugate, 0.1mg/mL
