Anti-PPM1D Purified
PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.
Product Specifications
Certification
RUO
Reactivity
Mouse, Human
Immunogen
Purified human PPM1D
Target Antigen
PPM1D
Clone
7E11/C5
Applications
ELISA (reported), ICC (reported), WB (QC tested), IHC-P (reported), FC-IC (verified)
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Western blotting: Recommended dilution: 1-2 μg/ml.Flow cytometry: Recommended dilution: 1-5 μg/ml. Intracellular staining.
Isotype
Mouse IgG1
Frequently Asked Questions
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