Chlorphenesin carbamate

Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133) . Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation[1]. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels[2]. Antinociceptive effect[3].

Product Specifications

CAS Number

[886-74-8]

Product Name Alternative

Maolate; U 19646

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/chlorphenesin-carbamate.html

Concentration

10mM

Purity

99.92

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC(COC1=CC=C(Cl)C=C1)COC(N)=O

Molecular Formula

C10H12ClNO4

Molecular Weight

245.66

Precautions

H315, H319, H320

References & Citations

[1]Ji-young Yu, et al. Relative bioavailability of generic and branded 250-mg and 500-mg oral chlorphenesin carbamate tablets in healthy Korean volunteers: a single-dose, randomized-sequence, open-label, two-period crossover trial. Clin Ther. 2009 Nov;31 (11) :2735-43.|[2]M Kurachi, et al. Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats. Jpn J Pharmacol. 1984 Sep;36 (1) :7-13. |[3]S Okuyama, et al. Antinociceptive effect of chlorphenesin carbamate in adjuvant arthritic rats. Res Commun Chem Pathol Pharmacol. 1987 Feb;55 (2) :147-60.