D-Tyrosine

D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[1][2].

Product Specifications

CAS Number

[556-02-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/d-tyrosine.html

Purity

98.96

Solubility

1 M HCl : 25 mg/mL (ultrasonic) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@H](CC1=CC=C(O)C=C1)C(O)=O

Molecular Formula

C9H11NO3

Molecular Weight

181.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Jisu Park, et al. D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity. Pigment Cell Melanoma Res. 2018 May;31 (3) :374-383.|[2]Cong Yu, et al. Inhibition of Biofilm Formation by D-tyrosine: Effect of Bacterial Type and D-tyrosine Concentration. Water Res. 2016 Apr 1;92:173-9.