Purified Anti-Human CD123 Antibody[6H6]
Product Specifications
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Abbreviation
CD123
Gene ID
3563
UniProt
P26951
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD123 protein
Target
IL3RA; CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; IL-3 Receptor alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R subunitalpha; IL-3RA; IL-3R-alpha; IL-3Receptoralpha; IL-3Rα; IL-4Receptoralpha; IL-5Receptoralpha; IL-6Receptoralpha; IL-7Receptoralpha; Interleukin-3 receptor subunit alpha; IL-3R&alpha
Clonality
Monoclonal
Clone
6H6
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Signal Transduction
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
Documents
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