Anti-ECS Antibody, Agarose immobilized

Goat Polyclonal Antibody specific to Agarose Immobilized Goat ECS

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Anti-Agarose Immobilized Goat ECS Goat Polyclonal Antibody

Gene ID

5651

UniProt

P98073

Cellular Locus

Membrane, Single-pass type II membrane protein

Host

Goat

Reactivity

Ecs

Immunogen

DDDDK conjugated to KLH.

Target

ECS, Agarose immobilized

Clonality

Polyclonal

Isotype

Whole IgG

Type

Antibody

Applications

Field of Research

Epitope Tags

Purification Method

Purified by peptide immuno-affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

Additionnal Information

Immunoprecipitation: use 15-25ul of gel slurry per 0.1-1mg of protein extract or lysate. <br><br>These are recommended concentrations. <br><br>End users should determine optimal concentrations for their applications.

Storage Conditions

This antibody is stable for at least one (1) year at 2-8°C.

Specificity

Antibody was affinity-purified on the peptide.

Formulation

Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide

Target Background

Enterokinase, also known as enteropeptidase, is a serine protease that catalyzes the hydrolysis of peptide bonds in proteins but, unlike other kinases, does not catalyze transfer of phosphate groups. Enterokinase cleaves proteins following a lysine at an enterokinase cleavage site, or ECS (Asp-Asp-Asp-Asp-Lys). In vivo, this cleavage results in trypsin-dependent activation of other pancreatic zymogens, such as chymotrypsinogen, proelastase, procarboxypeptidase and prolipase in the lumen of the gut.