Tea polyphenol

Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism[1].

Product Specifications

CAS Number

[84650-60-2]

UNSPSC

12352005

Hazard Statement

H225, H226, H319

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tea-polyphenol.html

Purity

99.0

Solubility

DMSO : 32.5 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

[Teapolyphenol]

Precautions

H225, H226, H319

References & Citations

[1]Suzuki J, et al. Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases. Mediators Inflamm. 2009;2009:494928.|[2]Chen D, et al. Tea polyphenols, their biological effects and potential molecular targets. Histol Histopathol. 2008 Apr;23 (4) :487-96.|[3]Mao X, et al. Oxidative stress-induced diseases and tea polyphenols. Oncotarget. 2017 Sep 14;8 (46) :81649-81661.|[4]Hui Zhou, et al. Regulation of autophagy by tea polyphenols in diabetic cardiomyopathy. J Zhejiang Univ Sci B. 2018 May;19 (5) :333-341.|[5]Xu Y, et al. Green tea polyphenols inhibit cognitive impairment induced by chronic cerebral hypoperfusion via modulating oxidative stress. J Nutr Biochem. 2010 Aug;21 (8) :741-8.|[6]Zhu WL, et al. Green tea polyphenols produce antidepressant-like effects in adult mice. Pharmacol Res. 2012 Jan;65 (1) :74-80. |[7]Chen X, et al. Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. World J Gastroenterol. 2009 Apr 21;15 (15) :1829-35.