SMARCA2 degrader-20
SMARCA2 degrader-20 is a PROTAC SMARCA2 degrader with a DC50 less than 100 nM in A549 cells[1].
Product Specifications
CAS Number
2568273-85-6
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smarca2-degrader-20.html
Smiles
OC1=CC=CC=C1C2=CC(C3=CN(C4CCN([C@H]5CC[C@@H](CNC6=CC(C(N(C7C(NC(CC7)=O)=O)C8=O)=O)=C8C=C6)CC5)CC4)N=C3)=C(N)N=N2
Molecular Formula
C38H41N9O5
Molecular Weight
703.79
References & Citations
[1]Nan J, et al. Smarca degraders and uses thereof, US20230072658A1, 2023-03-09
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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