1,2-Dilaurin

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55 (3), 1087-1090 (1990) .[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128 (2), 217-220 (1981) .

Product Specifications

CAS Number

[17598-94-6]

Product Name Alternative

(Rac) -1,2-Didodecanoylglycerol

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-2-dilaurin.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OCC(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O

Molecular Formula

C27H52O5

Molecular Weight

456.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhu X, et al. 1,2-diacylglycerol content and its arachidonyl-containing molecular species are reduced in sciatic nerve from streptozotocin-induced diabetic rats. J Neurochem. 1990 Sep;55 (3) :1087-90.|[2]Wieloch T, et al. Porcine pancreatic procolipase and its trypsin-activated form: lipid binding and lipase activation on monomolecular films. FEBS Lett. 1981 Jun 15;128 (2) :217-20.