DOT1L Recombinant Rabbit Monoclonal Antibody [PSH01-57]

Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Disrupter of telomere silencing protein 1 antibody DOT 1 antibody DOT1 antibody DOT1 like antibody DOT1 like histone H3 methyltransferase (S. cerevisiae) antibody DOT1 like histone H3 methyltransferase antibody DOT1 like histone H3K79 methyltransferase antibody DOT1 like protein antibody DOT1, S. cerevisiae, homolog of antibody DOT1-like protein antibody DOT1L antibody DOT1L_HUMAN antibody EC 2.1.1.43 antibody H3 K79 HMTase antibody H3 lysine-79 specific antibody H3-K79-HMTase antibody Histone H3 K79 methyltransferase antibody Histone H3 methyltransferase antibody Histone H3 methyltransferase DOT1-like antibody Histone H3-K79 methyltransferase antibody Histone lysine N methyltransferase H3 lysine 79 specific antibody Histone methyltransferase DOT1L antibody Histone-lysine N-methyltransferase antibody KIAA1814 antibody KMT4 antibody Lysine N methyltransferase 4 antibody Lysine N-methyltransferase 4 antibody

Abbreviation

Histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1-like protein Histone H3-K79 methyltransferase (H3-K79-HMTase) Lysine N-methyltransferase 4 DOT1L KIAA1814 KMT4

Swiss Prot

Q8TEK3 Human

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human DOT1/KMT4 aa 1- 500.

Isotype

IgG

Clone

PSH01-57

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

K-562 cell lysate, THP-1 cell lysate, HeLa cell lysate, 293T cell lysate, human testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 165 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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