Coelogin
Coelogin is an orally active osteoprotective agent which activates the ER-Erk and Akt-dependent signaling pathways that stimulate the osteoblastogenesis in osteoblast cells. Coelogin can be utilized in osteoporosis research[1].
Product Specifications
CAS Number
82358-31-4
UNSPSC
12352005
Target
Akt; ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/coelogin.html
Smiles
OC1=CC(CC2)=C3C4=C2C(OC)=C(OC)C(O)=C4COC3=C1
Molecular Formula
C17H16O5
Molecular Weight
300.31
References & Citations
[1]Prakash R, et al. Phenanthrenoid Coelogin Isolated from Coelogyne cristata Exerts Osteoprotective Effect Through MAPK-Mitogen-Activated Protein Kinase Signaling Pathway. Calcif Tissue Int. 2021 Jul;109 (1) :32-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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