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Coelogin

Coelogin is an orally active osteoprotective agent which activates the ER-Erk and Akt-dependent signaling pathways that stimulate the osteoblastogenesis in osteoblast cells. Coelogin can be utilized in osteoporosis research[1].

Product Specifications

CAS Number

82358-31-4

UNSPSC

12352005

Target

Akt; ERK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/coelogin.html

Smiles

OC1=CC(CC2)=C3C4=C2C(OC)=C(OC)C(O)=C4COC3=C1

Molecular Formula

C17H16O5

Molecular Weight

300.31

References & Citations

[1]Prakash R, et al. Phenanthrenoid Coelogin Isolated from Coelogyne cristata Exerts Osteoprotective Effect Through MAPK-Mitogen-Activated Protein Kinase Signaling Pathway. Calcif Tissue Int. 2021 Jul;109 (1) :32-43.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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