(p-Hydroxybenzyl) malonic acid

(p-Hydroxybenzyl) malonic acid is a hydroxyphenyl derivative capable of inhibiting insulin-induced lipogenesis in rat adipocytes with an IC50 value of 3.8 μM[1].

Product Specifications

CAS Number

[90844-16-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/p-hydroxybenzyl-malonic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C(O)=O)CC1=CC=C(O)C=C1

Molecular Formula

C10H10O5

Molecular Weight

210.18

Precautions

P261-P280-P302+P352

References & Citations

[1]Shechter Y, et al. Hydroxyphenyl acetate derivatives inhibit protein tyrosine kinase activity and proliferation in Nb2 rat lymphoma cells and insulin-induced lipogenesis in rat adipocytes. Mol Cell Endocrinol. 1991;80 (1-3) :183-192.