COX-1-IN-2
Product Specifications
UNSPSC Description
COX-1-IN-2 (compound 5h) is an anti-inflammatory agent with potent analgesic activity. COX-1-IN-2 exhibits a significant inhibitory effect on COX-1 (IC50=38.76 nM)[1].
Target Antigen
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-1-in-2.html
Smiles
FC1=CC=C(C2CC(C3=CC=C4C=CC=CC4=C3)=NN2C5=NC(C6=CC=C(OC)C=C6)=CS5)C=C1
Molecular Weight
479.57
References & Citations
[1]Mohammed, et al. "Discovery of new 2-(3-(naphthalen-2-yl)-4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024): 107372.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159561/COX-1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159561/
Clinical Information
No Development Reported
Curated Selection
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