COX-1-IN-2
COX-1-IN-2 (compound 5h) is an anti-inflammatory agent with potent analgesic activity. COX-1-IN-2 exhibits a significant inhibitory effect on COX-1 (IC50=38.76 nM) [1].
Product Specifications
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-1-in-2.html
Smiles
FC1=CC=C(C2CC(C3=CC=C4C=CC=CC4=C3)=NN2C5=NC(C6=CC=C(OC)C=C6)=CS5)C=C1
Molecular Formula
C29H22FN3OS
Molecular Weight
479.57
References & Citations
[1]Mohammed, et al. "Discovery of new 2- (3- (naphthalen-2-yl) -4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024) : 107372.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1
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