DSPC (Excipient)

Product Specifications

CAS Number

[816-94-4]

UNSPSC Description

DSPC Excipient (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC Excipient is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

Target Antigen

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dspc-excipient.html

Smiles

O=P([O-])(OCC[N+](C)(C)C)OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O

Molecular Weight

790.15

References & Citations

[1]Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.|[2]Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739.