6-T-5'-GMP
6-T-5'-GMP (6-Thioguanosine monophosphate) is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, Azathioprine.
Product Specifications
CAS Number
15867-02-4
Product Name Alternative
6-Thioguanosine monophosphate; 6-Thio-GMP
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/6-t-5-gmp.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=S)O[C@@H]1COP(O)(O)=O
Molecular Formula
C10H14N5O7PS
Molecular Weight
379.29
References & Citations
[1]Valerie NC, et al. NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. Cancer Res. 2016 Sep 15;76 (18) :5501-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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