Human PD-L1 inhibitor IV
Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1[1].
Product Specifications
CAS Number
[2135542-83-3]
UNSPSC
12352209
Target
PD-1/PD-L1
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/human-pd-l1-inhibitor-iv.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC(CN)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O
Molecular Formula
C80H113N25O27
Molecular Weight
1856.90
References & Citations
[1]Qiao Li, et al. Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor. Oncotarget. 2016 Oct 4;7 (40) :64967-64976.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
RPU56584-01 50 µg
Recombinant Human Neuropeptide Y Receptor Y1 (NPY1R)
Sign In for Pricing
View Details RPU56584-02 100 µg
Recombinant Human Neuropeptide Y Receptor Y1 (NPY1R)
Sign In for Pricing
View Details 
RPU56584-03 1 mg
Recombinant Human Neuropeptide Y Receptor Y1 (NPY1R)
Sign In for Pricing
View Details 474767 100 µL
ADCK2 (Uncharacterized AarF Domain-Containing Protein Kinase 2)
Sign In for Pricing
View Details K1900905 3x 1.0 µg
RPL11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details