Human PD-L1 inhibitor IV
Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1[1].
Product Specifications
CAS Number
[2135542-83-3]
UNSPSC
12352209
Target
PD-1/PD-L1
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/human-pd-l1-inhibitor-iv.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC(CN)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O
Molecular Formula
C80H113N25O27
Molecular Weight
1856.90
References & Citations
[1]Qiao Li, et al. Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor. Oncotarget. 2016 Oct 4;7 (40) :64967-64976.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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