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Human PD-L1 inhibitor IV

Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1[1].

Product Specifications

CAS Number

[2135542-83-3]

UNSPSC

12352209

Target

PD-1/PD-L1

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/human-pd-l1-inhibitor-iv.html

Purity

99.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC(CN)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O

Molecular Formula

C80H113N25O27

Molecular Weight

1856.90

References & Citations

[1]Qiao Li, et al. Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor. Oncotarget. 2016 Oct 4;7 (40) :64967-64976.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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