CH 5450
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM[1].
Product Specifications
CAS Number
252557-97-4
Product Name Alternative
Z-Ile-Glu-Pro-Phe-Ome
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Proteasome
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Z-Ile-Glu-Pro-Phe-Ome.html
Purity
98.19
Solubility
DMSO : ≥ 43 mg/mL
Smiles
O=C(OC)[C@@H](NC([C@H]1N(C([C@@H](NC([C@@H](NC(OCC2=CC=CC=C2)=O)[C@@H](C)CC)=O)CCC(O)=O)=O)CCC1)=O)CC3=CC=CC=C3
Molecular Formula
C34H44N4O9
Molecular Weight
652.73
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
ROR2 (ROR2/1911), CF488A conjugate, 0.1mg/mL
![FITC Anti-Mouse CD64/FcγRI Antibody[X54-5/7.1]](https://cdn.genprice.uk/products/763/68dd14b0061270361e7d3ec5/imageurl/e-ab-f1186c.webp)
FITC Anti-Mouse CD64/FcγRI Antibody[X54-5/7.1]
FITC Anti-Mouse CD64/FcγRI Antibody[X54-5/7.1]
FITC Anti-Mouse CD64/FcγRI Antibody[X54-5/7.1]
