PNB-001
PNB-001 is an orally active CCK2 selective ligand and antagonist. PNB-001 has anti-inflammatory and analgesic activities[1].
Product Specifications
CAS Number
[1528760-09-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pnb-001.html
Purity
99.65
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C(C2=CC=CC=C2)(N1CCC3=CC=CC=C3)O)Cl
Molecular Formula
C18H16ClNO2
Molecular Weight
313.78
Precautions
H302, H315, H319
References & Citations
[1]Lattmann E, et al. Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease. Medchemcomm. 2017 Feb 17;8 (3) :680-685.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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